55 Coronavirus Bulletin— 03/03/21
Research—The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection.
Paper hypothesized that aspirin use for primary cardiovascular disease prevention might have a protective effect on COVID-19 susceptibility and disease duration.
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Research—Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests.
Article reports an analysis of 133,816 samples collected between April-September 2020 and tested by Dorfman pooling for the presence of SARS-CoV-2
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Research—Arterial and venous thromboembolism in COVID-19: a study-level meta-analysis
This meta-analysis of 102 studies (n=64503) found patients admitted to the ICU for severe COVID-19 had a high risk of VTE. Further studies are needed to determine the specific effects of COVID-19 on the risk of thrombosis in less severe .
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Research—SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study
Objective to evaluate the performance of new lateral flow immunoassays (LFIAs) suitable for use in a national coronavirus disease 2019 (covid-19) seroprevalence programme (real time assessment of community transmission 2—React 2).
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Government decision—Information for Healthcare Professionals on COVID-19 Vaccine AstraZeneca
Click here for government information from Medicines & Healthcare products Regulatory Agency
Meta-Analysis—Immunosuppression as a risk factor for COVID‐19: a meta‐analysis
AIMS: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.
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Meta-Analysis—Immunosuppression as a risk factor for COVID‐19: a meta‐analysis
AIMS: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.
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Guidelines—A living WHO guideline on drugs to prevent covid-19
What is the role of drugs in preventing covid-19?Why does this matter?
Click here for BMJ guide
In a Personal View, author suggests increasing understanding of neutralising antibody response to COVID-19 might make identifying members of community at low risk of contracting & transmitting COVID-19 possible. A response to ethical arguments against the passports is also provided
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