57 Coronavirus Bulletin— 17/03/21

Worcestershire Health Libraries: 

57 Coronavirus Bulletin— 17/03/21

For additional support on accessing the publications below, visit www.wkp.nhs.uk

 Research—Genetic mechanisms of critical illness in COVID-19

GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK ICUs identified and replicated new genome-wide significant associations and identified potential targets for repurposing drugs. 

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 Research—Assessing risk for healthcare workers during the covid-19 pandemic

This article discusses the risk factors of older, male sex, and ethnic minority for healthcare workers and how risk assessment of the workplace, workforce, and individual, with adjustment to roles, can help reduce potential workplace hazards.

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 Research—Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study

Objective to establish whether there is any change in mortality from infection with a new variant of SARS-CoV-2, designated a variant of concern (VOC-202012/1) in December 2020, compared with circulating SARS-CoV-2 variants.

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Research—Clinical outcome of COVID-19 in patients with adult congenital heart disease.

The aim of this study was to collect clinical outcome data and to identify risk factors for a complicated course of COVID-19 in patients with ACHD

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Research— Cardiovascular Manifestations of COVID-19.

This review is intended to summarize current understanding of the CV manifestations of COVID-19 and to study the relationship between SARS-CoV-2 and CVDs and discuss possible mechanisms of action behind SARS-CoV-2 infection-induced damage to the CV system.

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 Audio Interview: The Implications of Changes in the Structural Biology of SARS-CoV-2

In this audio interview conducted on March 9, 2021, the NEJM editors are joined by structural biologist Jonathan Abraham to talk about the effect of new viral variants on the transmission of SARS-CoV-2 and on its potential to escape antibody-mediated protection.

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  Resources— New COVID-19 factsheet available in 22 languages from the European Lung FoundationThe European Lung Foundation has published a new COVID-19 factsheet pulling together all the information it has produced over the past year. 

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 Guidance—Safeguarding adults during the COVID-19 crisis

This guide to safeguarding adults during the COVID-19 pandemic has been updated (9th March 2021) to take into account the easing of lockdown restrictions.

Click here for Social Care Institute for Excellence guidance

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