Latest COVID-19 Research & Evidence - 170620

Research 

Title: Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

Description: In this study, the authors examined 7 lungs obtained during autopsy from patients who died from COVID-19, and 7 lungs from patients who died from acute respiratory distress syndrome secondary to H1N1.

Available from: https://www.nejm.org/doi/pdf/10.1056/NEJMoa2015432

Title: Death anxiety in the time of COVID-19: theoretical explanations and clinical implications

Description: Alongside other aims, this study sought to understand Terror Management Theory and its theoretical explanation of death anxiety in the context of COVID-19.

Available from: https://www.cambridge.org/core/services/aop-cambridge-core/con...

Title: Neuropsychiatric aspects of COVID-19 pandemic: A selective review

Description:  Here, the authors report the available evidence of neuropsychiatric morbidity during the current COVID-19 crisis. They also discuss the postulated neuronal mechanisms of the corona virus infection sequelae.

Available from: https://www.sciencedirect.com/science/article/pii/S1876201820303...

Guidelines

Title: Management of staff and exposed patients and residents in health and social care settings—updated

Description: This guidance provides advice on the management of staff and patients or residents in health and social care settings according to exposures, symptoms and test results.

Available from: https://www.gov.uk/government/publications/covid-19-management-of-e...

Title: Infection prevention and control (IPC) - updated

Description: This guidance outlines the infection prevention and control advice for health and social care providers involved in receiving, assessing and caring for patients who are a possible or confirmed case of COVID-19.

Available from: https://www.gov.uk/government/publications/wuhan-novel-coronavirus-in...

Expert Opinions

Title: Tackling UK’s mortality problem: covid-19 and other causes

Description: “We cannot reduce excess deaths unless we know what’s causing them”: the author explores under-reporting and the availability of statistical data during the COVID-19 pandemic.

Available from: https://www.bmj.com/content/bmj/369/bmj.m2295.full.pdf

Title: Obesity and covid-19: the role of the food industry

Description: Increasing evidence indicates that obesity is an independent risk factor for severe illness and death from covid-19. The authors discuss the urgency needed in tackling the obesity pandemic during the viral pandemic.

Available from: https://www.bmj.com/content/bmj/369/bmj.m2237.full.pdf

 For additional support with accessing the publications above, visit www.wkp.nhs.uk

Latest COVID-19 Research & Evidence — 10/06/20

Research 

Title: Quality and safety in the time of Coronavirus: design better, learn faster

Description: This article sets out quality improvement and patient safety science, applying them in a selection of approaches, methods and tools, which may be useful in crisis situations such as the current pandemic.

Available from: https://watermark.silverchair.com/mzaa051.pdf... 

Title: In-hospital airway management of COVID-19 patients

Description: In this review, the authors describe a practical, stepwise protocol for safe in-hospital management of patients with suspected or confirmed COVID-19 infection.

Available from: https://ccforum.biomedcentral.com/track/pdf/10.1186/s13054-020-03018-x

Title: Abrupt deterioration and pulmonary embolism in COVID-19: a case report

Description: A case is presented highlighting pulmonary embolism as an important complication of COVID-19 and the abruptness with which deterioration and widespread pulmonary infiltrates can develop.

Available from: https://www.rcpjournals.org/content/clinmedicine/early/2020/06/04...

Guidelines

Title: Remdesivir for treating hospitalised patients with suspected or confirmed COVID-19

Description: This review aims to establish the clinical effectiveness, safety and cost effectiveness of remdesivir in adults, young people and children hospitalised with suspected or confirmed COVID-19.

Available from: https://www.nice.org.uk/advice/es27/

Title: Perioperative care of patients with hip and major fragility fractures during the COVID-19 pandemic

Description: This document provides principles, recommendations and comments on the care given to patients with hip fracture, but these can be extended to the care of patients with fragility fractures at other sites.

Available from: https://icmanaesthesiacovid-19.org/consensus-statement-on-perioperative... 

Expert Opinions

Title: Responding to COVID-19: What’s the Problem?

Description: This commentary argues that the coronavirus pandemic should be considered as a transdisciplinary societal challenge that requires coordinated systemic thinking and actions in the context of uncertainty.

Available from: https://link.springer.com/content/pdf/10.1007/s11524-020-00456-4.pdf

Title: Telemedicine will not keep us apart in COVID-19 pandemic

Description: The authors describe their experiences in a high-flux rheumatological centre. More specifically, how lessons learnt on telemedicine protocols will be implemented within their next clinical practice reorganisation.

Available from: https://ard.bmj.com/content/annrheumdis/early/2020/06/05...

 For additional support with accessing the publications above, visit www.wkp.nhs.uk