Worcestershire Health Libraries: 55 Coronavirus Bulletin— 03/03/21

 

55 Coronavirus Bulletin— 03/03/21

 

Research—The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection.

Paper hypothesized that aspirin use for primary cardiovascular disease prevention might have a protective effect on COVID-19 susceptibility and disease duration.

Click here for access to full text

 

Research—Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests.

Article reports an analysis of 133,816 samples collected between April-September 2020 and tested by Dorfman pooling for the presence of SARS-CoV-2

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Research—Arterial and venous thromboembolism in COVID-19: a study-level meta-analysis

This meta-analysis of 102 studies (n=64503) found patients admitted to the ICU for severe COVID-19 had a high risk of VTE. Further studies are needed to determine the specific effects of COVID-19 on the risk of thrombosis in less severe .

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Research—SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study

Objective to evaluate the performance of new lateral flow immunoassays (LFIAs) suitable for use in a national coronavirus disease 2019 (covid-19) seroprevalence programme (real time assessment of community transmission 2—React 2).

Click here for full text

 

Government decision—Information for Healthcare Professionals on COVID-19 Vaccine AstraZeneca

Click here for government information from Medicines & Healthcare products Regulatory Agency

 

Meta-Analysis—Immunosuppression as a risk factor for COVID‐19: a meta‐analysis

AIMS: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.

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Meta-Analysis—Immunosuppression as a risk factor for COVID‐19: a meta‐analysis

AIMS: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.

Click here for full text

 

Guidelines—A living WHO guideline on drugs to prevent covid-19

What is the role of drugs in preventing covid-19?Why does this matter?

Click here for BMJ guide

 Article—The scientific and ethical feasibility of immunity passports

In a Personal View, author suggests increasing understanding of neutralising antibody response to COVID-19 might make identifying members of community at low risk of contracting & transmitting COVID-19 possible. A response to ethical arguments against the passports is also provided

Click here for full text article

 

 

We make every effort to ensure that the information we provide for you is the best, most appropriate and most recent available to us, but Worcestershire Health Libraries can make no warranty, express or implied, as to the accuracy of any information supplied. We take no responsibility for any action taken on the basis of this information.

 

54 Coronavirus Bulletin— 23/02/21

 

Worcestershire Health Libraries: 

54 Coronavirus Bulletin— 23/02/21

 

 

Article –The prognostic value of comorbidity for the severity of COVID-19: A systematic review and meta-analysis study.

  The main objective of the study is to provide additional data regarding the clinical characteristics of the patients diagnosed with COVID-19, and in particular to analyze the factors associated with disease severity, lack of improvement, and mortality.

Click here for full text article

 

Article—Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis.

Study aimed to compare paediatric COVID-19 disease characteristics, management and outcomes according to World Bank country income level and disease severity .

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Clinical trial—Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

A placebo-controlled, observer-blinded, pivotal efficacy trial, using either placebo or the BNT162b2 vaccine candidate (30 μg per dose).  The primary end points were efficacy of the vaccine against laboratory-confirmed Covid-19 and safety.

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A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia

Randomly assigned hospitalized adult patients with severe Covid-19 pneumonia in a 2:1 ratio to receive convalescent plasma or placebo. The primary outcome was the patient’s clinical status 30 days after the intervention, as measured on a six-point ordinal scale ranging from total recovery to death

Click here for full text trial

 

Tools—Coronavirus (COVID-19) risk assessment

QCovid® is a coronavirus risk prediction model, created by the University of Oxford, which NHS Digital are using to support the NHS coronavirus response

Click here to access tool

 

 

Research—Ethnic minority health staff are less likely to take up vaccine, early data show

A hospital trust in the Midlands has said that it is working to understand why some of its staff remain unvaccinated against covid-19

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Research—Real-time Assessment of Community Transmission (REACT) Study

Click here to REACT study website

 

Guidance—COVID-19 Response - Spring 2021

Click here for the government published COVID-19 Response - Spring 2021’, setting out the roadmap out of the current lockdown for England.

 

Technical report—Behavioural Insights research to support the response to COVID-19: a survey of implementation in the EU

This Technical Report presents evidence about the current status of Behavioural Insights (BI) research being conducted in the ten EU/EEA Member State

Click here for full report

 

We make every effort to ensure that the information we provide for you is the best, most appropriate and most recent available to us, but Worcestershire Health Libraries can make no warranty, express or implied, as to the accuracy of any information supplied. We take no responsibility for any action taken on the basis of this information.

 

53 Coronavirus Bulletin—16/02/21

 

Worcestershire Health Libraries: 

53 Coronavirus Bulletin—16/02/21

 

Article— Healthcare Workers' Knowledge, Attitude, and Practice Regarding Personal Protective Equipment for the Prevention of COVID-19.

Article aims to assess the knowledge, attitude, and practice (KAP) regarding personal protective equipment (PPE) among healthcare workers, along with a survey of the possible determinants. 

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Article — A box-shaped shielding device for reducing the risk of COVID-19 droplet infection during gastrointestinal endoscopic procedures.

This retrospective study investigated the utility of a box-shaped shielding device for reducing the risk of COVID-19 droplet infection during endoscopic procedures.

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Article— Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

We investigated the incidence of SARS-CoV-2 infection confirmed by polymerase chain reaction (PCR) in seropositive and seronegative health care workers attending testing of asymptomatic and symptomatic staff at Oxford University Hospital

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Guidance—Infection prevention and control and preparedness for COVID-19 in healthcare settings - sixth update

This document aims to provide guidance to healthcare facilities and healthcare providers on preparedness and infection prevention and control (IPC) measures for the management of possible and confirmed cases of COVID-19

To access guidance click here

 

Guidance — COVID-19 rapid guideline: delivery of radiotherapy

Click here for NICE guidance

 

Guidance—COVID-19 vaccination: information for healthcare practitioners

Click here for Government guidance

 

Guidance — COVID-19 rapid guideline: critical care in adults

Click here for NICE guidance

 

Diagnosis— COVID-19 in cancer patients: a systematic review.

This review aims to describe the risk of infection and developing severe COVID-19 in cancer patients

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Diagnosis—COVID-19 Diagnostic Clinical Decision Support: a Pre-Post Implementation Study of CORAL (COvid Risk cALculator).

Article describes describe the development, implementation, and outcomes of an inpatient diagnostic algorithm and clinical decision support system (CDSS) to evaluate

Access full text here

 

For additional support on accessing the publications above, visit www.wkp.nhs.uk

 

 We make every effort to ensure that the information we provide for you is the best, most appropriate and most recent available to us, but Worcestershire Health Libraries can make no warranty, express or implied, as to the accuracy of any information supplied. We take no responsibility for any action taken on the basis of this information.